Neurological manifestations of magnesium deficiency in infantile gastroenteritis and malnutrition.

نویسندگان

  • E H BACK
  • R D MONTGOMERY
  • E E WARD
چکیده

The syndrome of severe protein malnutrition in infants, complicated as it frequently is by refractory vomiting or frank gastro-enteritis, presents gross electrolyte disturbances. Most notable of these is potassium depletion and an accumulation of sodium (Hansen, 1956; Frenk, Metcoff, Gomez, Ramos-Galvan, Cravioto and Antonowicz, 1957; Waterlow and Mendes, 1957). In addition, magnesium deficiency has recently been demonstrated (Montgomery, 1960, 1961). Calcium-deficient tetany is occasionally seen, but less rarely neurological disturbances occur which are resistant to calcium therapy. These may take the form of generalized hypertonus with neck stiffness and carpopedal spasm, or of irregular muscle twitching, coarse tremors or generalized convulsions. They have usually been pre-terminal events in cases with grave electrolyte imbalance. Five cases are presented in which these neurological disorders were shown to be associated with low levels of serum magnesium. In three cases calcium was given parenterally without effect, and in all cases magnesium therapy was followed by a remission. Two of the cases survived.

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عنوان ژورنال:
  • Archives of disease in childhood

دوره 37  شماره 

صفحات  -

تاریخ انتشار 1962